Manny Pacquiao vs. Mario Barrios odds, prediction, betting line, time: July 19 fight picks from boxing expert

Mario Barrios will look to defend his WBC welterweight championship when he battles former champion Manny Pacquiao in a 12-round bout on Saturday. The main Pacquiao vs. Barrios fight card is set for approximately 8 p.m. ET from MGM Grand Garden Arena in Las Vegas. Barrios is coming off a 12-round split decision draw with Abel Ramos this past November. Pacquiao, meanwhile, will be entering the ring for the first time in nearly four years after losing a unanimous decision to Yordenis Ugas for the WBA (Super) welterweight championship on Aug. 21, 2021.

Barrios is a -275 favorite (risk $275 to win $100), while Pacquiao comes back at +210 in the latest Mario Barrios vs. Manny Pacquiao odds, from DraftKings Sportsbook. The over/under for number of rounds is 10.5, with the Over favored at -140 and the Under listed at +105. The fight not going the distance returns -125. Barrios winning by KO/TKO/DQ is the favored outcome at +135. Before making any Mario Barrios vs. Manny Pacquiao picks, be sure to see the boxing predictions from SportsLine’s Josh Nagel.

Nagel, who is the combat sports editor for SportsLine, is an experienced and successful boxing analyst. He previously served as SportsLine’s main boxing analyst and covered the sport for multiple outlets for more than 20 years. He has recently returned to his role as SportsLine’s top boxing analyst, and his recent winners include calling Dimitry Bivol (+110) to pull the slight upset of Artur Beterbiev in their February rematch. 

In April, he correctly called Jarron Ennis to beat Eimantas Stanionis by KO (+155), while also correctly predicting the Under 10.5 rounds (+165). He also correctly called Jake Paul by decision (-110) against Julio Cesar Chavez Jr. in June. He kept his hot streak going by recommending Katie Taylor (+170) against Amanda Serrano in their trilogy showdown just last week. Anyone following at sportsbooks and on betting apps could have seen huge returns.

Now, Nagel has studied Mario Barrios vs. Manny Pacquiao from every angle and revealed his top picks and best bets. You can only see his picks and analysis at SportsLine. Also be sure to see the latest DraftKings promo code, FanDuel promo code and BetMGM promo code to get even more value if you’re a new user. 

Why you should back Barrios

Barrios, 30, has held the WBC welterweight title since 2024. He won the vacant WBC interim welterweight title on Sept. 30, 2023, when he won a unanimous decision over Ugas. He had previously held the WBA regular version lightweight title from 2019 to 2021. He won the vacant WBC Continental Americas welterweight championship with an eighth-round knockout of Jovanie Santiago on Feb. 11, 2023.

He began his professional boxing career in 2013, and went on to win his first 26 matches. In 32 career fights, Barrios is 29-2-1. He has registered 18 knockouts and 11 wins by decision. His only losses came within a one-year span, when he was knocked out by Gervonta Davis on June 26, 2021, and lost a unanimous decision to Keith Thurman on Feb. 5, 2022. Barrios goes by several nicknames, including Golden Boy. See which fighter to back here.

Why you should back Pacquiao

Pacquiao, 46, known as Pac Man, is the only boxer in history to win 12 world championships in eight different weight classes. He won the lineal championship in four different weight classes — flyweight, featherweight, super featherweight and light welterweight. Last month, Pacquiao was inducted into the International Boxing Hall of Fame. He is the third boxer from the Philippines to receive the honor.

Pacquiao began his professional boxing career in 1995 at the age of 15, defeating Edmund Enting Ignacio by unanimous decision. He went on to win his first 11 bouts, before being knocked out by Rustico Torrecampo on Feb. 9, 1996. He has gone on to register 62 wins with eight losses and two draws. He has 39 wins by knockout and 23 by decision. See which fighter to back here.

How to make Pacquiao vs. Barrios picks

Nagel likes the Over 9.5 total rounds. He’s also locked in a confident money-line picks and a method-of-victory prop that returns plus-money. Head to SportsLine to see what it is. 

Who wins Mario Barrios vs. Manny Pacquiao and which method of victory prop could bring a big return? Join SportsLine here to see which bets you need to make for the fight, all from the accomplished veteran combat sports analyst who has consistently delivered winners.