CRISPR-edited stem cells reveal hidden causes of autism
To allow studying the genetic causes of autism spectrum disorder, a Kobe University research team created a bank of 63 mouse embryonic stem cell lines containing the mutations most strongly…
Disruption of a single amino acid in a cellular protein makes breast cancer cells behave like stem cells
Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumour growth by increasing cancer stemness in an oestrogen independent manner. Targeting vimentin and/or the long noncoding RNA…
ERR-gamma ‘trains’ stomach stem cells to become acid-producing cells
Common conditions such as indigestion and heartburn as well as peptic ulcers, autoimmune gastritis and stomach and esophageal cancers have one thing in common – they involve disruptions of the…
Apple Logic Pro for iPad 2 Gets AI-Powered Session Players and Stem Splitters in a Big Update
Apple hosted its Let Loose event on Tuesday where it unveiled the new iPad Pro and iPad Air models alongside the Apple Pencil Pro. But amid all the hardware announcements,…
Using stem cell-derived heart muscle cells to advance heart regenerative therapy
Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function. However, the risk of arrhythmias following this procedure is reportedly high. In…
Decoding cell fate: Key mechanism in stem cell switch identified
Stem cells can differentiate to replace dead and damaged cells. But how do stem cells decide which type of cell to become in a given situation? Using intestinal organoids, the…
Potential glaucoma treatment strategy to guide stem cells to the retina
Glaucoma is one of the leading causes of blindness worldwide, and vision loss, due to the loss of retinal ganglion cells (RGCs), cannot currently be reversed with any treatment. Some…
Some benefits of exercise stem from the immune system
The connection between exercise and inflammation has captivated the imagination of researchers ever since an early 20th-century study showed a spike of white cells in the blood of Boston marathon…