Targeted alpha therapy: Breakthrough in treating refractory skin cancer
Metastatic melanoma, also known as stage IV melanoma, is a type of skin cancer that spreads to other parts of the body. It is one of the most aggressive forms…
New therapy may effectively control HIV in Uganda
A multi-national, multi-institutional study led by Weill Cornell Medicine investigators found little natural resistance to a new HIV therapy called lenacapavir in a population of patients in Uganda. The study,…
Gene therapy for rare epilepsy shows promise in mice
Dravet syndrome and other developmental epileptic encephalopathies are rare but devastating conditions that cause a host of symptoms in children, including seizures, intellectual disability, and even sudden death. Most cases…
Microbial therapy offers new hope for vitiligo patients
A natural compound derived from gut-friendly bacteria significantly slows the progression of vitiligo and may restore pigmentation, reports a new Northwestern University pre-clinical study in mice. The findings could offer…
New discovery enables gene therapy for muscular dystrophies, other disorders
Gene therapy can effectively treat various diseases, but for some debilitating conditions like muscular dystrophies there is a big problem: size. The genes that are dysfunctional in muscular dystrophies are…
Sleeping for 2: Insomnia therapy reduces postpartum depression, study shows
While many people believe that poor sleep during pregnancy is inevitable, new research has determined that cognitive behavioral therapy for insomnia (CBTi) while pregnant can not only improve sleep patterns…
Single-dose gene therapy is potentially life-changing for adults with hemophilia B
Adults with hemophilia B saw their number of bleeding episodes drop by an average of 71 percent after a single infusion of gene therapy, according to the results of an…
Cognitive behavioral therapy enhances brain circuits to relieve depression
Cognitive behavioral therapy, one of the most common treatments for depression, can teach skills for coping with everyday troubles, reinforce healthy behaviors and counter negative thoughts. But can altering thoughts…
Is long-term beta-blocker therapy needed after a heart attack?
The cardiovascular safety of interrupting beta-blocker could not be shown in comparison to continuation in patients with a history of myocardial infarction (MI) and there was no benefit to the…
Machine learning approach helps researchers design better gene-delivery vehicles for gene therapy
Gene therapy could potentially cure genetic diseases but it remains a challenge to package and deliver new genes to specific cells safely and effectively. Existing methods of engineering one of…