Big impacts from small changes in cell
Tiny things matter — for instance, one amino acid can completely alter the architecture of the cell. Researchers at the Universities of Göttingen and Warwick investigated the structure and mechanics…
Scientists unveil complete cell map of a whole mammalian brain
For the first time ever, an international team of researchers has created a complete cell atlas of a whole mammalian brain. This atlas serves as a map for the mouse…
First-in-human clinical trial of CAR T cell therapy with new binding mechanism shows promising early responses
Early results from a Phase I clinical trial of AT101, a new CAR T cell therapy that uses a distinct binding mechanism to target CD19, show a 100 percent complete…
Decoding cell fate: Key mechanism in stem cell switch identified
Stem cells can differentiate to replace dead and damaged cells. But how do stem cells decide which type of cell to become in a given situation? Using intestinal organoids, the…
Restoring the function of a human cell surface protein in yeast cells
Yeast cells are widely used to study G protein-coupled receptors (GPCRs), a large group of cell surface proteins in humans. However, several of these proteins lose their function when introduced…