How cells recognize and repair DNA damage
Whenever cells divide, there is a high risk of damage to the genetic material. After all, the cell has to duplicate its entire genetic material and copy billions of genetic…
Turning brain cells on using the power of light
University of Rochester researchers have demonstrated a noninvasive method using BL-OG, or bioluminescent optogenetics, that harnesses light to activate neurons in the brain. The ability to regulate brain activation could…
Fever drives enhanced activity, mitochondrial damage in immune cells
Fever temperatures rev up immune cell metabolism, proliferation and activity, but they also — in a particular subset of T cells — cause mitochondrial stress, DNA damage and cell death,…
Drug bypasses suppressive immune cells to unleash immunotherapy
By recruiting the immune system to combat tumor cells, immunotherapy has improved survival rates, offering hope to millions of cancer patients. However, only about one in five people responds favorably…
Hexagonal perovskite oxides: Electrolytes for next-generation protonic ceramic fuel cells
A new study presents a significant advancement in fuel cell technology. Researchers from Tokyo Tech identified hexagonal perovskite-related Ba5R2Al2SnO13 oxides (R = rare earth metal) as materials with exceptionally high…
Scientists discover new T cells and genes related to immune disorders
Researchers led by Yasuhiro Murakawa at the RIKEN Center for Integrative Medical Sciences (IMS) and Kyoto University in Japan and IFOM ETS in Italy have discovered several rare types of…
Fasting primes the immune system’s natural killer cells to better fight cancer, new study in mice finds
Periods of fasting reprogram the immune system’s natural killer cells to better fight cancer, according to a new study in mice from researchers at Memorial Sloan Kettering Cancer Center (MSK).…
ERR-gamma ‘trains’ stomach stem cells to become acid-producing cells
Common conditions such as indigestion and heartburn as well as peptic ulcers, autoimmune gastritis and stomach and esophageal cancers have one thing in common – they involve disruptions of the…
Using stem cell-derived heart muscle cells to advance heart regenerative therapy
Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function. However, the risk of arrhythmias following this procedure is reportedly high. In…
AI tool creates ‘synthetic’ images of cells for enhanced microscopy analysis
Observing individual cells through microscopes can reveal a range of important cell biological phenomena that frequently play a role in human diseases, but the process of distinguishing single cells from…