Drug pollution alters salmon migration
In the largest study of its kind to date, a team of international researchers has investigated how pharmaceutical pollution affects the behaviour and migration of Atlantic salmon. The study, led…
Groundbreaking light-driven method to create key drug compounds
Traditionally, chemists have relied on well-established but limiting methods to synthesize these molecules. The new research, co-authored by Kevin Brown, the James F. Jackson Professor of Chemistry in the College,…
Anti-amyloid drug shows signs of preventing Alzheimer’s dementia
An experimental drug appears to reduce the risk of Alzheimer’s-related dementia in people destined to develop the disease in their 30s, 40s or 50s, according to the results of a…
Scientists solve mystery of how the drug retinoic acid works to treat neuroblastoma
Neuroblastoma is a solid tumor that occurs in children. When high-risk, the disease has a poor prognosis. Decades ago, adding the drug retinoic acid to neuroblastoma treatment increased survival by…
Drug may prevent some migraine attacks in children and teens
For children and teens living with migraine, there may be a new preventive treatment, according to a preliminary study released today, February 26, 2025, that will be presented at the…
Scientists design peptides to enhance drug efficacy
A team of scientists has developed a groundbreaking approach using specially designed peptides to improve drug formulations. This innovative method significantly enhances anti-tumor efficacy, as demonstrated in leukemia models. The…
New drug to prevent migraine may start working right away
A drug recently approved to prevent migraine may start working right away, according to a study published in the December 23, 2024, online issue of Neurology®, the medical journal of…
Scientists discover a ‘Goldilocks’ zone for DNA organization, opening new doors for drug development
In a discovery that could redefine how we understand cellular resilience and adaptability, scientists at Scripps Research have unlocked the secret interactions between a primordial inorganic polymer of phosphate known…
New paradigm of drug discovery with world’s first atomic editing?
In pioneering drug development, the new technology that enables the easy and rapid editing of key atoms responsible for drug efficacy has been regarded as a fundamental and “dream” technology,…
AI and quantum mechanics team up to accelerate drug discovery
Drug discovery is much like working a jigsaw puzzle. The chemical compounds behind drug molecules must be shaped to fit with the proteins in our bodies to produce therapeutic effects.…